. 2019 Jun 18;8(2):83. doi: 10.3390/antibiotics8020083

Table 1.

Comparison of the various coordinate regulatory systems described in this review.

Regulator Name.	Organism	Regulator Type	Antibiotics Regulated	Type of Regulation	Ref.
FscRI	Streptomyces albus	PAS-LuxR family	Candicidin	Positive direct	[37]
FscRI	Streptomyces albus	PAS-LuxR family	Antimycins	Positive direct	[37]
CcaR	Streptomyces clavuligerus	SARP-type	Cephamycin C	Positive direct	[38]
CcaR	Streptomyces clavuligerus	SARP-type	Clavulanic acid	Positive direct	[38]
GdmRIII	Streptomyces autolyticus	TetR-family	Geldanamycin	Antagonistic direct	[39]
GdmRIII	Streptomyces autolyticus	TetR-family	Elaiophylin	Antagonistic direct	[39]
JadR1	Streptomyces venezuelae	Atypical OmpR-family	Jadomycin	Antagonistic direct	[40]
JadR1	Streptomyces venezuelae	Atypical OmpR-family	Chloramphenicol	Antagonistic direct	[40]
PG-Cl₂/PG-Cl	Pseudomonas protegens	Chemical	2,4-diacetylphloroglucinol	Dose dependant	[41]
PG-Cl₂/PG-Cl	Pseudomonas protegens	Chemical	Pyoluteorin	Dose dependant	[41]
Crp	Streptomyces coelicolor	Crp-Fnr family	Actinorhodin	Global	[42]
			Undecylprodiogisin
			Calcium-dependant antibiotic
			yellow-pigmented polyketide
MtrA	Streptomyces coelicolor	OmpR-family	Actinorhodin	Global	[35,43]
	Streptomyces coelicolor		Undecylprodiogisin
	Streptomyces venezuelae		Chloramphenicol
	Streptomyces venezuelae		Jadomycin