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. 2019 Jun 5;9(6):219. doi: 10.3390/biom9060219

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Polyphenols from different subclasses showing more pronounced pAkt-inhibition. The columns represent means of the residual phosphorylation (in %) with standard deviations. Statistically significant inhibitions were observed for the flavones luteolin and apigenin, the flavonols fisetin and quercetin, the dibenzo-α-pyrone urolithin A and the stilbenoid resveratrol (n = 3–6), ** p < 0.01. The difference between the effects of luteolin and resveratrol was statistically significant as well, ^## p < 0.01 (one-way ANOVA with Tukey HSD test).