Table 6.
Effects of EEIH on oxidative and nitrosative stress in renal tissue of LPS-treated mice.
| Group | Dose (mg/kg) | SOD (U/mg prot) |
GSH (µmol/g prot) |
MDA (nmol/mg prot) |
NO (µmol/g prot) |
|---|---|---|---|---|---|
| NC | − | 34.26 ± 1.79 | 10.59 ± 0.97 | 2.50 ± 0.28 | 0.24 ± 0.06 |
| MC | − | 22.32 ± 2.92 ### | 6.57 ± 0.53 ### | 5.43 ± 0.43 ### | 1.01 ± 0.05 ### |
| DEX | 1.8 | 30.82 ± 3.21 ** | 12.69 ± 0.78 *** | 2.99 ± 0.45 *** | 0.29 ± 0.06 *** |
| EEIH | 1.25 | 45.07 ± 3.77 *** | 14.08 ± 0.70 *** | 4.47 ± 0.42 ** | 0.26 ± 0.03 *** |
| 2.5 | 42.78 ± 3.14 *** | 15.88 ± 1.11 *** | 3.51 ± 0.32 *** | 0.25 ± 0.06 *** | |
| 5.0 | 47.59 ± 3.79 *** | 16.89 ± 0.68 *** | 2.80 ± 0.25 *** | 0.24 ± 0.05 *** |
The values are presented as the means ± SD (n = 5). Significant differences compared to the normal control group (NC) are designated as ### p < 0.001; those compared to the model control group (MC) as ** p < 0.01 and *** p < 0.001. DEX: dexamethasone (positive control).