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. 2019 Jun 25;20(12):3093. doi: 10.3390/ijms20123093

Figure 2.

Figure 2

Anti-histone IgG levels in control and rheumatoid arthritis subjects. IgG levels against native (Nat) and citrullinated (Cit) histone H1 (A), histone H2A (B), histone H2B (C), histone H3 (D), and histone H4 (E) were measured by ELISA for controls, CCP− rheumatoid arthritis (RA) and CCP+ RA. Graphs depict average absorbance values in arbitrary units (AU) with SEM. Groups were compared by ANOVA. For all graphs, n = 39 controls, 41 CCP− RA, 70 CCP+ RA; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.