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. 2019 Jun 25;20(12):3093. doi: 10.3390/ijms20123093

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Anti-histone IgG levels in CCP⁺ rheumatoid arthritis do not significantly correlate with genotypes at rs2240335. IgG levels against native and citrullinated histone H1 (A), histone H2A (B), histone H2B (C), histone H3 (D) and histone H4 (E) measured by ELISA in CCP⁺ rheumatoid arthritis subjects homozygous for the G or T allele at rs2240335 were compared by t-test. For all panels, graphs depict average absorbance values in arbitrary units (AU) ± SEM, no comparisons were significant, and n = 46 GG and 24 TT.