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. 2019 Jun 12;20(12):2860. doi: 10.3390/ijms20122860

Figure 1.

Figure 1

HAC1 gene in Baker’s yeast with a 252-nt intron flanked by two exons (whose coding sequences are pink-shaded), with part of the intron forming base-pair interaction with 5’UTR to inhibit translation initiation. 3’BE is a cis-acting bipartite element signaling for HAC1 pre-mRNA to be carried to discrete foci of Ire1p oligomers to be spliced [26]. The red ‘UGA’ within the intron stops occasional translation of the unspliced mRNA. The blue-shaded UACUAAG resembles a branchpoint site (BPS, consensus UACUAAC), but its deletion does not affect HAC1 pre-mRNA splicing [27].