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The specialized pro-resolving mediators (SPMs) biosynthetic route and physiologic actions. EPA, eicosapentaenoic acid; DPA, docosapentaenoic acid; DHA, docosahexaenoic acid; Elovl5, ELOVL fatty Acid Elongase 5; Elovl2, ELOVL fatty Acid Elongase 2; Fads2, Fatty Acid Desaturase 2.
