Figure 1.

Membrane trafficking pathways at the trans-Golgi network (TGN): (A) a schematic showing the post-Golgi trafficking pathways (red arrows) and the retrograde recycling pathways (black arrows) from the plasma membrane and endosomal/lysosomal compartments back to the TGN; (B) the distinct trafficking pathways at the TGN are regulated by specific cargo adaptor proteins including adaptor protein (AP) complexes (AP-1 in red, AP-3 in blue, AP-4 in orange); and (C) monomeric Golgi-localized, γ ear-containing, Arf-binding proteins (GGA1-3 in brown).