Table 1.
Cohort characteristics.
| Variables | Overall Cohort (n = 113) |
No Sarcopenia (n = 86) |
Sarcopenia (n = 27) |
p |
|---|---|---|---|---|
| Age (years) | 80 ± 6 | 80 ± 6 | 79 ± 6 | 0.6 |
| Male | 77 (68%) | 56 (65%) | 21 (78%) | 0.28 |
| Diabetes | 61 (54%) | 48 (56%) | 13 (48%) | 0.41 |
| Previous cardiovascular events | 61 (54%) | 43 (53%) | 18 (67) | 0.12 |
| eGFR * (mL/min/1.73 m2) | 27 ± 6 | 28 ± 5 | 25 ± 3 | 0.25 |
| Creatinine | 2.5 ± 1.2 | 2.6 ± 1.0 | 2.8 ± 1.3 | 0.29 |
| Creatinine Clearance (mL/min/1.73 m2) | 27 ± 14 | 28 ± 15 | 19 ± 12 | 0.01 |
| Criteria for sarcopenia | ||||
| Reduced handgrip strength (%) | 63 | 52 | 100 | <0.0001 |
| Reduced MAMC ** (%) | 34 | 13 | 100 | <0.0001 |
| Reduced Gait Speed Test (%) | 69 | 63 | 88 | 0.028 |
| Physical performance | ||||
| PAS *** | 7 ± 5 | 7 ± 5 | 4 ± 6 | 0.0014 |
| SPPB **** | 7 ± 4 | 8 ± 4 | 6 ± 3.75 | 0.0008 |
| IADL scale ***** | 5.0 ± 1.0 | 5.0 ± 1.0 | 5 ± 1.8 | 0.016 |
| Frail patients (%) ****** | 50 (45%) | 33 (38%) | 17 (63%) | 0.023 |
| Depression (%) | 33 | 67 | 32 | 0.16 |
| Depression score | 9.1 ± 6.0 | 8.3 ± 5.5 | 11.8 ± 7.1 | 0.008 |
* eGFR: estimated glomerular filtration rate; ** MAMC: mid arm muscle circumference. *** PAS: physical activity scale; **** SPPB: short physical performance battery; ***** IADL: instrumental activities of daily life (Lawton’s scale), ****** According to Frailty phenotype.