Table 1.

Mutations of genes encoding fibroblast growth factor receptors (FGFRs) in melanoma and other skin cancers.

Cancer	Gene	Encoded Substitution/Fusion	Refs
acanthosis nigricans	FGFR3	K650M	[108,109]
adenoid seborrheic keratoses	FGFR3	R248C	[106]
squamous cell carcinoma	FGFR3	G380R	[110]
melanoma	FGFR1	P252R/S/T	[113]
	FGFR2	S24F, V77M, E160A, H213Y, E219K, G227E, V248D, R251Q, G271E, G305R, T370R, W474X, E475K, D530N, E574K, E636K, M640I, I642V, A648T, S688F, G702S, P708S, R759X, R759Q, L770V	[122]
	FGFR3	FGFR3-TACC3 fusion	[104]
	FGFR3	P451S	[119]
	FGFR4	G388R	[118,119]