Figure 5.

Origin of tumour samples. The primary tumour samples were grade 4 (Pr1), grade 3 (Pr2), grade 4 with sarcomatoid differentiation (Pr4), and grade 3 (Pr3). The venous tumour thrombus of 10 cm length extending to the inferior vena cava was grade 2 (VT). The metastasis in the lingula of the left lung was grade 4 with sarcomatoid differentiation (M1). The metastasis in the dorsal apex, the lower lobe of the left lung, was grade 4 (M2). The metastasis in the lateral basal, the lower lobe of the right lung, had a tumour grade 3 (M3). The metastasis in the upper lobe of the left lung was grade 4 with rhabdoid differentiation and was obtained by lobectomy after PEG-interferon treatment (M4). The haematoxylin and eosin -stained images were made based on 400× magnification.