T2DM |
Type 2 Diabetes Mellitus |
eNOS |
Endothelial NO Synthase |
GWAS |
Genome Wide Association Studies |
AMPK |
5’AMP-activated protein kinase |
BH4 |
Tetrahydrobiopterin |
ROS |
Radical Oxygen Species |
NO |
Nitric Oxide |
AGEs |
Advanced Glycosylated End products |
mtDNA |
Mitochondrial DNA |
SNP |
Single nucleotide polymorphism |
EWAS |
Epigenome-wide association studies |
TSS |
Transcription Start Site |
TF |
Transcription Factor |
DNMT |
DNA-methyltransferase |
MeCpG |
methylated CpG Binding-Protein |
HDAC |
Histone deacetylase |
HMT |
Histone methyltransferase |
HAT |
Histone acetyltransferase |
KMT |
Lysine methyltransferase |
ncRNA |
Non-coding RNA |
rRNA |
Ribosomal RNA |
tRNA |
Tranfer RNA |
snRNA |
small nuclear RNA |
snoRNA |
small nucleolar RNA |
siRNAs |
small interfering RNA |
piRNAs |
piwi-associated RNA |
miRNA, miRs |
micro RNA |
lncRNA |
Long non-coding RNA |
hs-CRP |
high-sensitive C-reactive protein |
AHBA |
alpha-hydroxybutyric acid |
LGPC |
linoleonylglycerophosphorcholine |
ECs |
endothelial cells |
PTHM |
Post-translational histone modifications |
HAEC |
human aortic endothelial cells |
MMPs |
matrix metalloproteinases |
LINE-1 |
Long Intersperted Nuclear Element 1 |
HRGEC |
human renal glomerular endothelial cells |
EPCs |
endothelial progenitor cells |
PBMC |
peripheral blood mononuclear cells |
SIRT1 |
Sirtuin 1 |
FOXO1 |
Forkhead box O1 |
TSA |
Tricostatin A |
ECFCs |
Endothelial Colony Forming Cells |
HMGB1 |
High mobility group box 1) |
TZD |
thiazolidinediones |
SU |
Sulfonylureas |
MODY |
Maturity-Onset Diabetes of the Young |
HNF1A |
hepatocyte nuclear factor 1 homeobox A |
Met |
Metformin |
OCT1 |
Organic Cation Transporter 1 |
PARP |
Poly (ADP ribose) Polymerase |