Table 3.
Blood and urine data (mean ± sd) after 2, 12 and 18 months of treatment. See text for description.
| NEAA-100% | EAA-30% | EAA-100% | StD | Casein-Prot | Casein-AA | |||
|---|---|---|---|---|---|---|---|---|
| Blood 2 months | F | p | ||||||
| Glucose (mg/dL) | 108.3 ± 6.7 *^ | 111.7 ± 7.9 * | 122.04 ± 8.1 | 127.3 ± 9.6 | - | - | 8.47 | 0.000 |
| Erythrocytes (M/μL) | 7.75 ± 1.93 | 8.01 ± 1.32 | 9.04 ± 0.58 | 9.13 ± 0.29 | - | - | 1.69 | 0.210 |
| Hemoglobin (g/dL) | 10.23 ± 2.37 *^ | 11.46 ± 2.15 *^ | 14.18 ± 1.16 | 14.8 ± 0.46 | - | - | 8.04 | 0.002 |
| NLR | 1.88 ± 1.02 *^ | 1.64 ± 0.93 *^ | 0.68 ± 0.26 | 0.67 ± 0.25 | - | - | 3.95 | 0.028 |
| Albumin (g/L) | 22.58 ± 1.68 *^ | 24.75 ± 1.56 * | 26.8 ± 1.83 | 28.66 ± 2.57 | - | - | 9.03 | 0.000 |
| Creatinine (μmol/L) | 25.92 ± 4.54 | 24.95 ± 3.9 | 22.8 ± 1.75 | 23.82 ± 1.89 | - | - | 0.86 | 0.480 |
| Haptoglobin (mg/mL) | 0.02 ± 0.01 *^ | 0.04 ± 0.01 *^ | 0.13 ± 0.02 * | 0.18 ± 0.02 | - | - | 113.83 | 0.000 |
| Urine 3 months | ||||||||
| Albumin (g/L) | 0.9 ± 0.4 *^ | 0.8 ± 0.6 *^ | 2.2 ± 0.4 | 1.8 ± 0.3 | - | - | 12.19 | 0.000 |
| Creatinine (μmol/L) | 5502 ± 443 *^ | 5653 ± 520 *^ | 3956 ± 824 | 4066 ± 1027 | - | - | 7.49 | 0.002 |
| Blood 12 months | F | p | ||||||
| Glucose (mg/dL) | - | - | 119.3 ± 11.4 | 124.3 ± 19.4 | 127.25 ± 14 | 113.25 ± 4.3 | 1.04 | 0.40 |
| Erythrocytes (M/μL) | - | - | 9.65 ± 0.62 | 9.93 ± 0.37 | 9.28 ± 0.33 | 9.8 ± 0.28 | 2.23 | 0.124 |
| Hemoglobin (g/dL) | - | - | 13.35 ± 1.02 | 14.4 ± 1.5 | 14.32 ± 0.3 | 14.4 ± 0.2 | 1.54 | 0.243 |
| NLR | - | - | 0.71 ± 0.1 | 0.72 ± 0.12 | 0.65 ± 0.07 | 0.67 ± 0.14 | 0.45 | 0.723 |
| Albumin (g/L) | - | - | 29.7 ± 1.7 | 30.88 ± 2.1 | 46.2 ± 8.03 *^ | 31.6 ± 6.6 ^ | 11.09 | 0.000 |
| Creatinine (μmol/L) | - | - | 46.9 ± 2.3 | 42.9 ± 5.7 | 72.33 ± 12.7 *^ | 57.0 ± 12.4 | 9.75 | 0.000 |
| Haptoglobin (mg/mL) | - | - | 0.10 ± 0.04 * | 0.15 ± 0.07 | 4.53 ± 0.15 *^ | 4.97 ± 0.06 *^ | 3968 | 0.000 |
| Urine 12 months | ||||||||
| Albumin (g/L) | - | - | 2.13 ± 0.23 | 1.94 ± 0.21 | 1.3 ± 0.19 *^ | 1.02 ± 0.35 *^ | 21.46 | 0.000 |
| Creatinine (μmol/L) | - | - | 3581 ± 526 | 3832 ± 364 | 2934 ± 355 *^ | 2595 ± 222.7 *^ | 11.13 | 0.000 |
| Blood 18 months | t | p | ||||||
| Glucose (mg/dL) | - | - | 127.2 ± 8.3 | 133.4 ± 12.6 | - | - | 0.919 | 0.385 |
| Erythrocytes (M/μL) | - | - | 9.73 ± 0.25 | 9.97 ± 1.06 | - | - | 0.493 | 0.635 |
| Hemoglobin (g/dL) | - | - | 14.23 ± 0.15 | 14.87 ± 1.4 | - | - | 1.016 | 0.339 |
| NLR | - | - | 0.95 ± 0.2 * | 1.44 ± 0.08 | - | - | 5.087 | 0.000 |
| Albumin (g/L) | - | - | 29.1 ± 0.7 * | 27.4 ± 0.78 | - | - | 2.332 | 0.04 |
| Creatinine (μmol/L) | - | - | 38.3 ± 2.69 | 37.8 ± 1.45 | - | - | 0.366 | 0.724 |
| Haptoglobin (mg/mL) | - | - | 0.33 ± 0.15 * | 0.56 ± 0.16 | - | - | 2.268 | 0.05 |
| Urine 18 months | ||||||||
| Albumin (g/L) | - | - | 1.58 ± 0.99 * | 3.49 ± 0.87 | - | - | 3.241 | 0.01 |
| Creatinine (μmol/L) | - | - | 2954.9 ± 927 | 3421.7 ± 670 | - | - | 0.913 | 0.388 |
NLR = Neutrophils lymphocytes ratio. ANOVA and Bonferroni t-test: * p < 0.05 vs. StD, ^ p < 0.05 vs. EAA-100%.