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. 2019 Apr 30;9(2):48. doi: 10.3390/diagnostics9020048

Figure 1.

Figure 1

HAMP expression is reduced in liver hepatocellular carcinoma (HCC) and low HAMP expression is linked to higher cancer metastasis stage code and poor disease-free status. (A) HAMP expression in HCC tumors was significantly decreased relative to adjacent liver tissue (p < 0.0001). (B) Histogram showing HAMP expression in liver hepatocellular cancer. The 2−ΔΔCt approach was used to calculate HAMP expression, and expression in each patient is given as the tumor (T, n = 50)/normal (N, n = 50) ratio; (C) Low HAMP expression is associated with high cancer metastasis in HCC patients (p = 0.0121). (D) Low HAMP expression is associated with poor disease-free status in HCC patients, according to a Kaplan–Meier analysis of HCC (n = 320, log rank test, p = 0.0431).