Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jun 20;8(6):617. doi: 10.3390/cells8060617

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The effect of licochalcone A (LA) on airway hyper-responsiveness (AHR) and cell counts in bronchoalveolar lavage fluid (BALF) of asthmatic mice. (A) On days 1–3 and 14, mice were sensitized with ovalbumin (OVA) by intraperitoneal injection (IP) and challenged with 2% OVA inhalation (IH) on days 14, 17, 20, 23, and 27. One hour before the OVA challenge or methacholine inhalation, mice were treated with LA or DMSO (n = 12 mice/group). (B) AHR was measured as a percentage of lung resistance (RI) from baseline normal (N) and (C) dynamic lung compliance (C_dyn). (D) Inflammatory cells were measured and the percentage of inflammatory cells in the BALF presented. (E) Inflammatory cells and total cells were measured in BALF. Three independent experiments were analyzed, and data were presented as mean ± SEM. * P < 0.05 compared to the OVA control group. ** P < 0.01 compared to the OVA control group.