Table 2.
Correlation between TfR1 expression and clinicopathological features of the 201 CRC patients
| Clinicopathological features | No. of patients | Positive (%) | Negative (%) | P-value |
|---|---|---|---|---|
| Gender | ||||
| Male | 125 | 71 (56.8) | 54 (43.2) | 0.879 |
| Female | 76 | 44 (57.9) | 32 (42.1) | |
| Age (years) | ||||
| ＜60 | 88 | 50 (56.8) | 38 (43.2) | 0.920 |
| ≥60 | 113 | 65 (57.5) | 48 (42.5) | |
| Tumor size (cm)a | ||||
| ＜5 | 108 | 68 (63.0) | 40 (37.0) | 0.090 |
| ≥5 | 92 | 47 (51.1) | 45 (48.9) | |
| Tumor site | ||||
| Right colon | 52 | 20 (38.5) | 32 (61.5) | 0.017 |
| Transverse colon | 15 | 10 (66.7) | 5 (33.3) | |
| Left colon | 58 | 37 (63.8) | 21 (36.2) | |
| Rectum | 76 | 48 (63.2) | 28 (36.8) | |
| Differentiationa | ||||
| Well | 20 | 14 (70.0) | 6 (30.0) | 0.008 |
| Moderate | 148 | 91 (61.5) | 57 (38.5) | |
| Poor | 28 | 9 (32.1) | 19 (67.9) | |
| Depth of tumor invasion | ||||
| T1＋T2 | 30 | 22 (73.3) | 8 (26.7) | 0.053 |
| T3＋T4 | 171 | 93 (54.4) | 78 (45.6) | |
| Lymph node | ||||
| N0 | 86 | 60 (69.8) | 26 (30.2) | 0.002 |
| N1-2 | 115 | 55 (47.8) | 60 (52.2) | |
| Distant metastasisa | ||||
| M0 | 99 | 66 (66.7) | 33 (33.3) | 0.006 |
| M1 | 99 | 47 (47.5) | 52 (52.5) | |
| Vascular invasion | ||||
| Absent | 142 | 94 (66.2) | 48 (33.8) | ＜0.001 |
| Present | 59 | 21 (35.6) | 38 (64.4) | |
| TNM stagea | ||||
| Ⅰ＋Ⅱ | 68 | 47 (69.1) | 21 (30.9) | 0.013 |
| Ⅲ＋Ⅳ | 130 | 66 (50.8) | 64 (49.2) |
Notes: aThere are some missing data in tumor size, differentiation, distant metastasis and TNM stage of these 201 patients as mentioned in Table 1. P values < 0.05 shown in bold.