Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jul 10;11:6457–6466. doi: 10.2147/CMAR.S200234

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 Han et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

The expression level of FGF5, FGFR1 and MAPK signaling pathway associated proteins (p-MEK2, MEK2, p-ERK, ERK, p-MNK1, and MNK1) on control or FGF5 knockout OS cells without or with rFGF5 treatment and detected by Western blot. The results showed that FGF5 activiated the MAPK signaling. *** P <0.001 vs. Crl; ^### P <0.001 vs rFGF5-

Abbreviations: Crl, control; KO, knockout; FGF5, fibroblast growth factor-5; FGFR1, FGF receptor-1; rFGF5, recombinant FGF5; OS, osteosarcoma; MAPK, mitogen-activated protein kinase; GAPDH, glyceraldehyde 3-phosphate dehydrogenase.