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. 2019 Jul 10;11:6457–6466. doi: 10.2147/CMAR.S200234

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© 2019 Han et al.

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The expression levels of FGF5, FGFR1 and MAPK signaling pathway associated proteins (p-MEK2, MEK2, p-ERK, ERK, p-MNK1, and MNK1) in control and FGF5 knockout nude mice detected by Western blot. The results showed that FGF5 knockout dampen MAPK signaling in vivo. *** P <0.001

Abbreviations: Crl, control; KO, knockout; FGF5, fibroblast growth factor-5; FGFR1, FGF receptor-1; MAPK, mitogen-activated protein kinase; MAPK, mitogen-activated protein kinase; GAPDH, glyceraldehyde 3-phosphate dehydrogenase.