The supragingival biofilm in early childhood caries: clinical and laboratory protocols and bioinformatics pipelines supporting oral metagenomics, metatranscriptomics and metabolomics studies of the oral microbiome

. Author manuscript; available in PMC: 2019 Jul 15.

Published in final edited form as: Methods Mol Biol. 2019;1922:525–548. doi: 10.1007/978-1-4939-9012-2_40

i. MAST [28]	zero-inflated log-normal distribution
ii. Two-part Logistic Beta model [29, 30]	Bernoulli and Beta distribution
iii. Two-part Wilcoxon Rank Sum test [31]	Bernoulli and normal (rank)
iv. Zero-inflated negative binomial model [32, 33]	zero-inflated negative binomial
v. LEfSe [24]	normal
vi. Kruskal-Wallis test [34]	normal (rank)