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Butyrylcholine esterase (BuChE) inhibitory activity of 1–3.
| Compound | % inhibition at 6.25 µM | IC50 (µM) |
|---|---|---|
| 1 | 30.71 ± 0.21 ** | n.d. |
| 2 | 10.53 ± 1.01 ** | n.d. |
| 3 | 3.44 ± 0.09 * | n.d. |
| Galantamine | 10.34 ± 0.21 * | n.d. |
Results are given as mean ± SEM of three independent experiments performed in triplicate; n.d. = not determined. * p < 0.05; ** p < 0.01.
