CRC	colorectal cancer
CEA	carcinoembryonic antigen
EVs	extracellular vehicles
MVBs	multivesicular bodies
miRNAs	micro-RNAs
UTR	untranslated region
GOFs	gain of oncogenic functions
FU	5-fluorouracil
TME	tumor microenvironment
CAFS	cancer-associated fibroblasts
ECM	extracellular matrix constituents
TGF β	transforming growth factor β
PDGF	platelet derive growth factor
MCP1	monocyte chemotactic protein 1
IGF	insulin-like growth factor
FGF-2	fibroblast growth factor 2
PGE	prostaglandin E
ROS	reactive oxygen species
MDSC	myeloid-derived suppressor cells
TREG–T	regulatory cells
Th2	type 2 helper
uPA	urokinase-type plasminogen activator
ADM	adrenomedullin
MMPs	matrix metalloproteinases