Table 3.
Patients with ≥ 1 infection vs. no infection
| Infection (N = 148) | No infection (N = 222) | p value | |
|---|---|---|---|
| Age (years) at first hospitalization (median, IQR) | 5.9 years (3.1, 10.5) | 6.6 years (3.5, 11.3) | 0.008 |
| Sex (n, %) | 0.486 | ||
| Male | 94 (63.5) | 133 (59.9) | |
| Race/ethnicity (n, %) | 0.185 | ||
| White | 59 (47.2) | 86 (46.2) | |
| Hispanic | 29 (23.2) | 33 (17.7) | |
| Black | 21 (16.8) | 49 (26.3) | |
| Other | 16(12.8) | 18(9.7) | |
| Clinical pattern of NS (n, %) | 0.002 | ||
| Steroid sensitive-infrequently relapsing | 29 (19.6) | 75 (33.8) | |
| Steroid sensitive-frequently relapsing | 26 (17.6) | 32 (14.4) | |
| Steroid sensitive-steroid dependent | 31 (21.0) | 57 (25.7) | |
| Steroid-resistant | 53 (35.8) | 46 (20.7) | |
| Congenital or infantile | 4 (2.7) | 1 (0.5) | |
| Biopsy diagnosis (n, %) | 0.441 | ||
| Minimal change disease (± mild mesangial hypercellularity) | 48 (32.4) | 63 (28.4) | |
| FSGS or FGGS | 38 (25.7) | 47 (21.2) | |
| Membranous, MPGN, others | 9 (6.1) | 15 (6.8) | |
| No biopsy | 53 (35.8) | 97 (43.7) | |
| Baseline eGFR ml/min/1.73m2 (median, IQR) | 129.5 (99.0, 173.1) | 128.9 (95.0, 166.4) | 0.633 |
| Number of hospitalizations (median, IQR) | 2 (1,3.5) | 1 (1,2) | <0.001 |
| Overall hospital days (median, IQR) | 10(6,22) | 5 (3,8) | <0.001 |
| ICU days (median, IQR) | 0 (0, 0) | 0 (0, 0) | <0.001 |
NS nephrotic syndrome, eGFR estimated glomerular filtration rate, ICU Intensive Care Unit, FGGS focal global glomerulosclerosis, FSGS focal segmental glomerulosclerosis, MPGN membranoproliferative glomerulonephritis