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. 2019 Jun 19;20(12):2999. doi: 10.3390/ijms20122999

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Correlations between endogenous PARP1 activity and V’O_2max (A,B), DNA strand breaks 90 min after radiation and PARP1 activity 3 h after radiation (C,D), and endogenous PARP1 activity and γH2AX (E,F). Linear regression shows significant negative correlation between PARP1 activity and V’O_2max before exercise (A) as well as between DNA repair and PARP1 activity after acute exercise (D). A positive significant correlation was found between PARP1 activity and γH2AX (F) after exercise but not before (E). n = 12 subjects in each plot (six trained and six untrained). Statistical significance means a significant linear relationship between x and y. The p values were calculated from an F test and are displayed in each figure.

Correlations between endogenous PARP1 activity and V’O_2max (A,B), DNA strand breaks 90 min after radiation and PARP1 activity 3 h after radiation (C,D), and endogenous PARP1 activity and γH2AX (E,F). Linear regression shows significant negative correlation between PARP1 activity and V’O_2max before exercise (A) as well as between DNA repair and PARP1 activity after acute exercise (D). A positive significant correlation was found between PARP1 activity and γH2AX (F) after exercise but not before (E). n = 12 subjects in each plot (six trained and six untrained). Statistical significance means a significant linear relationship between x and y. The p values were calculated from an F test and are displayed in each figure.