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The rabbit in vivo cartilage trauma model. (A) The spring-loaded impact device for biomechanically defined force administration is fixed to the femur to avoid a shift of the indenter tip during the impact. (B) Both medial and lateral condyles were impacted. The impact sites are demonstrated by encirclement. (C) After 12 weeks, the animals were euthanized and the femoral condyles were harvested.
