Figure 1.

The expression of keratin 23 in primary human hepatocytes varies between different donors. (A) Gene expression analysis of keratins in primary human hepatocytes. Shown are the reads per kilobase million (RPKM) values of keratins from seven independent donors. (B) Differential expression of keratins in chronic hepatitis C patients (CHC) with low and high interferon-stimulated genes (ISG) induction compared with HCV-negative patients. Depicted are the differential expression of keratins in CHC patients with a low ISG response, compared with HCV-negative patients (left) and the differential expressions of keratins in CHC patients with a high ISG response compared with HCV negative patients (right). (FDR, false discovery rate).