Table A1.

Sequences of the oligonucleotides used for the single-guide RNA (sgRNA) vector cloning and for the sequencing of the genomic DNA (gDNA) of the CRISPR/Cas 9 KO cell lines.

KRT23 KO Oligos
specification	sequence
KRT23_Oligo #1_fwd	GTCGTCTCCCACCGGCTGGTGCCATTTCAGGATG GTTTCGAGACGTG
KRT23_Oligo #1_rev	CACGTCTCGAAACCATCCTGAAATGGCACCAGCCGGTGGGAGACGAC
KRT23_Oligo #2_fwd	GTCGTCTCCCACCGCAGTACAGCACGGTGAGTCAGTTTCGAGACGTG
KRT23_Oligo #2_rev	CACGTCTCGAAACTGACTCACCGTGCTGTACTGCGGTGGGAGACGAC
KRT23 KO gDNA primers for sequencing
specification	sequence
KRT23_gRNA1_left	ACCATGCAGAATCTCAACGAC
KRT23_gRNA1_right	TGGAAATTGTCTTCTGGACTCA
KRT23_gRNA2_left	ACTGTGCAGAGCAGACAAGGT
KRT23_gRNA2_right	GGAAAGTGAGAGTTGTCCCAAG