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Tissue distribution of (A) paclitaxel (PTX) and (B) everolimus (EVER) in female Nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mice bearing MDA-MB-231-H2N BC xenografts (HER2mod/EGFRmod) after single intravenous administration of dual-targeted PTX+EVER-loaded nanoparticles (Dual-NPs) or free PTX+EVER combination at a PTX-equivalent dose of 15 mg/kg and EVER-equivalent dose of 7.5 mg/kg. (n = 5).
