Skip to main content
. 2019 Jun 21;11(6):365. doi: 10.3390/toxins11060365

Figure 1.

Figure 1

The α-lobe in C3-like toxins. Superposition of six C3-like toxins showing a compact N-terminal substructure that encompasses four α-helices. The ARTT loop (ADP-ribosyl-turn-turn) is a catalytic region that is responsible for the target substrate recognition and is shown at the bottom right of the overlaid structures. The superposed structures include C3 exotoxin (PDB:1G24) and C3bot2 (PDB:1R45) from C. botulinum, C3lim (PDB:3BW8) from C. limosum, C3cer (PDB:4XSG) from B. cereus, C3larvin (PDB:4TR5) from P. larvae, and C3stau2 (PDB:1OJQ) produced by S. aureus.