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Inter-domain motif proximity. Identification of domains based on geometric criteria by the MOE 2018 algorithm, where the α3 and α4a helices of the N-domain (in red ribbons) are part of the C-domain (in blue ribbons) in C2-like toxins. The yellow oval highlights the special proximity of the α1 of the C-domain with the α3/4-loop of the N-domain.
