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. 2019 Jun 21;11(6):364. doi: 10.3390/toxins11060364

Table 1.

A review of the effects of ergot alkaloids and/or heat stress on follicular dynamics.

Alkaloid (µg/kg/day) Heat Stress Average Daily Gain Animal Effect Source
N/A N/A N/A Beef heifer Decrease in the diameter and number of large follicles. [59]
N/A N/A N/A Beef heifer Decrease in the diameter and number of large follicles. [60]
N/A Possibly, grazing from April to Sept. in Arkansas Reduced Mature beef cows Diameter of the largest follicle tended to be smaller. No difference in the number of small or large follicles. Number of medium sized follicles reduced. [61]
10,310 total; 3910 ergovaline Possibly, barn temperature. 27 °C and average THI 1 72 Reduced, same intake Beef heifer Number of medium sized follicles reduced. No difference in the number of small or large follicles or diameter of largest follicle. [50]
1900 ergovaline Yes, between 25 °C and 31 °C N/A, reduced intake Beef heifer Decrease in the diameter and number of large follicles. [62]
1000 total; 421 ergovaline Yes, average THI 88 Same Beef heifer Decrease in the diameter and number of small and large follicles. [63]

1 THI = temperature-humidity index; THI = (1.8 × Tdb +32) – ((0.55 – 0.0055 × RH) × (1.8 × Tdb – 26.8)); Tdb = dry bulb temperature (°C), and RH = relative humidity. Recovery (non-life threatening, 75) and emergency (high-risk, 85) thresholds as described by Hahn [64].