Table 1.
Complementarity determining regions (CDRs) of different mycolactone specific antibodies identified by phage and yeast display using the two selection strategies described in the text.
| Clone ID | LCDR3 | HCDR1 | HCDR2 | HCDR3 | Abundance after Selection 1 | Abundance after Selection 2 |
|---|---|---|---|---|---|---|
| M3_B11 | MQARQTPPT | GGTFSSYA | IIPIFGTA | ARVRWEPQSGYYHGMDVW | 100% | 18% |
| M3_A10 | MQARQTPPT | GGTFSSYA | IIPIFGTA | ARVRWVPQSGYYHGMDVW | 0% | 30% |
| M3_E1 | AAWDDSLNGPA | GYTFTSYG | YTFTSYG | ARVGGMGGDYVEYW | 0% | 20% |
| M3_B12 | SSYSSSSSYV | GGTFSSYA | IIPIFGTA | LIVGATTGGDAFDIW | 0% | 16% |
| M3_B4 | LLYYGGDWV | GGTFSSYA | IIPIFGTA | AAVGLDAFDIW | 0% | 4% |
| M3_C6 | MQGTHWPPT | GGTFSSYA | IIPIFGTA | AITDGIFDIW | 0% | 4% |
| M3_A2 | AAWDDRLNGVV | GGTFSSYA | IIPIFGTA | ARGSGYYDSSGYHWYFDLW | 0% | 2% |
| M3_C11 | SSYAGSNGSV | GGTFSSYA | IIPIFGTA | AVYSSGWYGGTTEDYW | 0% | 2% |
| M3_E9 | MQGTHWPPT | GGTFSSYA | IIPIFGTA | ARVAYYYGSGSYSFDYW | 0% | 2% |
| M3_B10 | SSYSSSSSYV | GGTFSSYA | IIPIFGTA | AAADYYDSSGYYYGGVEEHW | 0% | 2% |