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. 2019 Jun 19;11(6):355. doi: 10.3390/toxins11060355

Figure 2.

Figure 2

Predicted amino acid sequences of representative sequences of ICK peptides screened in RNA extracts from L. intermedia, L. gaucho and L. laeta. A fraction of L. intermedia containing LiTx1, LiTx2 and LiTx3 proved to be toxic against a lepidopteran larva [7]. A LiTx3 orthologue (Li1b) was heterologously expressed and also showed toxic activity in sheep blowflies [64]. Asterisks indicate conserved cysteine residues and the lines below the alignments indicate the pattern of disulphide bonds that form the inhibitor cystine knot motif [64].