Table 9.
Summary of linear dose-response meta-analyses of prospective studies on fish intake and CVD, CHD, stroke, T2DM, CRC, breast cancer.
| Authors, Year, Reference | No. of Studies | Each Increment Intake Per Day | RR (95% CI) | I2 Statistic | p-Value for Heterogeneity | Begg’s or Egger’s Test p-Value |
|---|---|---|---|---|---|---|
| Jayedi 2018 [51] | 8 | 20 g | CVD mortality 0.96 (0.94–0.98) | 0.00% | 0.620 | NR |
| Bechthold 2017 [17] | 15 | 100 g | CHD 0.88 (0.79–0.99) | 40.00% | 0.060 | NS |
| Zheng 2012 [52] | 17 | 15 g | CHD mortality 0.94 (0.90–0.98) | 63.10% | 0.000 | NR |
| Bechthold 2017 [17] | 15 | 100 g | Stroke 0.86 (0.75–0.99) | 25.00% | 0.180 | NR |
| Schwingshackl 2017 [18] | 15 | 100 g | T2DM 1.09 (0.93–1.28) | 84.00% | NR | NS |
| Vieira 2017 [20] | 11 | 100 g | CRC 0.89 (0.80–0.99) | 0.00% | 0.520 | NS |
| Schwingshackl 2018 [21] | 16 | 100 g | CRC 0.93 (0.85–1.01) | 12.00% | 0.320 | 0.910 |
| Zheng 2013 [53] | 11 | 15 g | Breast cancer 1.00 (0.97–1.03) | 64.00% | 0.001 | NS |
| Wu 2016 [41] | 13 | 120 g | Breast cancer incidence 1.07 (0.94–1.21) | 33.30% | NR | 0.100/0.089 |
CVD, cardiovascular disease; CHD, coronary heart disease; T2DM, type 2 diabetes mellitus; CRC, colorectal cancer; RR, relative risk; NR, not reported; NS, not significant.