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. 2019 Jul 10;15:1939–1950. doi: 10.2147/NDT.S203870

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© 2019 Geng et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

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Multivariate statistical analysis between the LPS-induced depression and healthy Control groups at ESI+: (A) principal component analysis (PCA) scores plot; (B) partial least squares-discriminate analysis (PLS-DA) scores plot; (C) statistical validation of the PLS-DA model through 200× permutation testing; and (D) pair-wise orthogonal projections to latent structures discriminant (OPLS-DA) scores plot. Multivariate statistical analysis between the LPS-induced depression and healthy Control groups at ESI−: (E) PCA scores plot; (F) PLS-DA scores plot; (G) statistical validation of the PLS-DA model through 200×permutation testing; and (H) OPLS-DA scores plot.

Abbreviations: LPS, lipopolysaccharide; ESI, electrospray ionization.