In a validation data set of 2692 patients with Alzheimer disease and related dementia, the deep learning–based models showed high note events–level classification of 6-month, 1-year, and 2-year mortality, achieving areas under the receiver operating characteristic curve of 0.978 (95% CI, 0.977-0.978) for the 6-month model, 0.956 (95% CI, 0.955-0.956) for the 1-year model, and 0.943 (95% CI, 0.942-0.944) for the 2-year model.