Table 1. Relationship of the Ki-67 Index with Demographics, Presurgical Data, and Outcomes in the Study Population.
| No. (%)a | Median Ki - 67 Index (Q25 - 75) | P Valueb | |
|---|---|---|---|
| Age at surgery, y | 0.036 | ||
| < 30 | 12 (24.5) | 2.25 (1.05 - 5) | |
| ≥ 30 | 37 (75.5) | 1 (0.9 - 1.5) | |
| Gender | 0.323 | ||
| Female | 35 (71.4) | 1. (0.9 - 1.5) | |
| Male | 14 (28.6) | 1.5 (0.97 - 2.62) | |
| Tumor type | 0.7 | ||
| Microadenoma (< 10 mm) | 3 (6.1) | 2 (0.9 - 2) | |
| Macroadenoma (≥ 10 mm) | 46 (93.9) | 1.5 (0.9 - 1.5) | |
| Extent of tumor resection c | 0.968 | ||
| Total | 27 (64.3) | 1.5 (1 - 1.5) | |
| Partial | 15 (35.7) | 1.5 (0.9 - 3) | |
| Tumor invasion | |||
| Suprasellar | 16 (38.1) | 1.5 (0.9 - 3.75) | 0.596 |
| Infrasellar | 4 (9.5) | 1.25 (0.92 - 2.62) | 0.918 |
| Cavernous sinus | 11 (26.2) | 1 (0.9 - 1.5) | 0.098 |
| Tumor secretory type | 0.843 | ||
| Pure GH | 22 (46.8) | 1.25 (0.97 - 1.62) | |
| Mixed GH/PRL | 25 (53.2) | 1.5 (0.9 - 1.75) | |
| Postoperative remission three-month d | 17 (40.5) | 1.5 (1 - 2) | 0.613 |
| Final remission e | 15 (45.5) | 1.5 (1 - 2) | 0.618 |
| Remission with drugs f | 7 (41.2) | 3 (0.9 - 8.5) | 0.193 |
Abbreviations: GH, growth hormone; PRL, prolactin.
a Number of patients.
b Significance level set at P < 0.05.
c Data available for 42 patients.
d Data available for 41 patients.
e Data available for 33 patients.
f Data from 16 patients.