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. 2019 May 29;10(6):414. doi: 10.3390/genes10060414

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) The Kaplan–Meier estimates of the OS for high-risk and low-risk patient cohorts grouping by the four-pseudogene signature (N = 94). The OS differences between the two groups were determined by the two-sided log-rank test. It can be concluded that higher risk scores are significantly associated with worse OS (p < 0.0001). (B) ROC analysis of sensitivity and specificity for the four-pseudogene signature in predicting the OS of patients for 3-, 5-, and 8-years. (C) The distribution of four-pseudogene risk score, patients’ survival status and pseudogene expression signature were analyzed. As the risk score rising, the patients had a shorter survival time, more death events and the expression value of four pseudogenes ascended or decreased. OS: overall survival.