TABLE 2.
Target and organ at risk doses
EBUS-upstaged# | EBUS-downstaged¶ | |||
EBUS-TBNA+PET | PET | EBUS-TBNA+PET | PET | |
PTV D95% Gy | 58.1±2.7 | 16.3±3.3 | 59.7±0.6 | 58.6±1.1 |
Mean heart Gy | 10.9±7.9 | 8.4±7.4 | 12.2±3.5 | 15.9±8.4 |
Mean oesophagus Gy | 18.5±5.6 | 12.0±5.7 | 16.6±10.4 | 29.1±5.2 |
Lung NTCP % | 9.6±2.0 | 7.6±1.5 | 12.6±5.3 | 18.3±5.3 |
Data are presented as mean±sd. EBUS: endobronchial ultrasound; TBNA: transbronchial needle aspiration; PET: positron emission tomography; PTV: planning target volume; D95%: treatment volume receiving >95% of planned dose; NTCP: normal tissue complication probability. #: EBUS-positive/PET-negative, n=4, dose was changed; ¶: EBUS-negative/PET-positive, n=4 (because two out of six patients where EBUS identified a lesser extent of lymph node disease could not reasonably be encompassed within a radical radiotherapy field when planned based on PET alone and therefore plans were not created), potential change in dose.