Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Computational docking of ketoconazole (A, CYP26A1; B, CYP26B1) or R115866 (A, CYP26A1 or B, CYP26B1) supports the reported type II binding interactions observed for CYP26A1 and suggests a similar binding interaction will occur with CYP26B1. The sp2 hybridized nitrogen was located within 3 Å of the heme iron in all cases. Portions of the protein structure are not displayed for added clarity.
