Table 1.
A collection of top twenty upregulated and downregulated miRNAs detected by next-generation sequencing in prostate tissues (carrageenan group vs blank control group)
| miRNA | BaseMean | Log2(fold change) | P | Type |
|---|---|---|---|---|
| rno-miR-155-5p* | 7.741 | 5.205 | <0.001 | Up |
| rno-miR-501-3p* | 2186.460 | 5.076 | <0.001 | Up |
| rno-miR-1956-3p* | 3.715 | 4.710 | 0.006 | Up |
| rno-miR-212-5p* | 109.202 | 4.057 | <0.001 | Up |
| rno-miR-146a-3p* | 14.179 | 3.554 | <0.001 | Up |
| rno-miR-223-5p* | 4.443 | 3.550 | 0.002 | Up |
| rno-miR-370-3p | 2.897 | 3.457 | 0.014 | Up |
| rno-miR-340-5p* | 326.544 | 3.265 | <0.001 | Up |
| rno-miR-6215* | 2.621 | 3.233 | 0.0362 | Up |
| rno-miR-511-3p* | 3.968 | 3.181 | 0.013 | Up |
| rno-miR-184* | 192.557 | 3.165 | 0.013 | Up |
| rno-miR-210-3p* | 85.837 | 3.155 | <0.001 | Up |
| rno-miR-146b-5p* | 2201.022 | 3.053 | <0.001 | Up |
| rno-miR-542-3p | 125.935 | 3.027 | <0.001 | Up |
| rno-miR-351-3p | 44.609 | 2.910 | 0.008 | Up |
| rno-miR-511-5p* | 20.242 | 2.888 | <0.001 | Up |
| rno-miR-382-5p | 7.463 | 2.843 | 0.012 | Up |
| rno-miR-450b-3p | 4.201 | 2.813 | 0.023 | Up |
| rno-miR-146a-5p* | 4459.610 | 2.810 | <0.001 | Up |
| rno-miR-541-5p | 109.988 | 2.627 | 0.004 | Up |
| rno-miR-33-5p* | 365.461 | −7.861 | <0.001 | Down |
| rno-miR-136-5p* | 20.234 | −6.805 | <0.001 | Down |
| rno-miR-19a-3p* | 8.844 | −5.697 | <0.001 | Down |
| rno-miR-150-5p | 1275.055 | −5.005 | <0.001 | Down |
| rno-miR-130a-3p* | 774.472 | −4.961 | <0.001 | Down |
| rno-miR-883-5p* | 25.518 | −3.852 | <0.001 | Down |
| rno-miR-874-5p* | 4.954 | −3.809 | 0.003 | Down |
| rno-miR-324-5p | 24.101 | −3.802 | <0.001 | Down |
| rno-miR-542-5p* | 12.549 | −3.738 | <0.001 | Down |
| rno-miR-19b-3p* | 45.434 | −3.517 | 0.001 | Down |
| rno-miR-1247-5p | 15.468 | −3.384 | <0.001 | Down |
| rno-miR-301a-3p | 11.139 | −3.190 | 0.008 | Down |
| rno-miR-547-5p* | 2.531 | −3.145 | 0.021 | Down |
| rno-miR-186-3p* | 4.322 | −3.139 | 0.010 | Down |
| rno-let-7i-3p* | 10.928 | −3.118 | 0.002 | Down |
| rno-miR-26a-3p* | 3.129 | −3.105 | 0.019 | Down |
| rno-miR-196b-3p* | 2.454 | −3.099 | 0.025 | Down |
| rno-miR-141-3p | 66.361 | −2.998 | 0.008 | Down |
| rno-miR-211-5p | 5.806 | −2.982 | 0.004 | Down |
| rno-miR-141-5p* | 11.748 | −2.957 | 0.006 | Down |
*The differentially expressed miRNAs overlapped in CAR versus BC and CAR versus NS. BaseMean: the average levels of miRNA expression; log2(fold change): the 2-logarithm value of the expression fold change of certain miRNA; NS: normal saline group; CAR: carrageenan group; BC: blank control group