Table 1. Patient characteristics and laboratory results for patients with laboratory-confirmed measles during the outbreak in the Gothenburg area, Sweden, December 2017–January 2018 (n = 28).
Patient | Infection typea | Age group (years) |
Doses of measles vaccine received | Days from onset of rash to sampling | Symptoms | Fulfilled EU criteria for confirmed caseb | Infected others |
---|---|---|---|---|---|---|---|
1 | N | 21–30 | 0 | 3 | R F K C Z | Yes | Yes |
2 | N | 31–40 | 0 | 3 | R F C | Yes | Yes |
3 | N | 0–10 | 0 | 2 | R F C Z | Yes | Yes |
4 | N | 0–10 | 0 | 1 | R F C | Yes | No |
5 | N | 31–40 | 0 | 0 | R F C | Yes | No |
6 | N | 0–10 | 0 | 0 | R F C | Yes | No |
7 | N | 0–10 | 0 | 0 | R F C | Yes | Yes |
8 | N | 51–60 | 0 | 4 | R F K C | Yes | Yes |
9 | N | 31–40 | 0 | 4 | R F C | Yes | No |
10 | N | 0–10 | 0 | 1 | R F K C | Yes | No |
11 | N | 0–10 | 0 | 1 | R F K C | Yes | No |
12c | N | 31–40 | 0 | 5 | R F K C | Yes | No |
13 | B | 21–30 | 1d | 1 | R F | No | No |
14 | B | 31–40 | 2 | 1 | R F | No | No |
15 | B | 31–40 | 2 | 0 | R F | No | No |
16 | B | 31–40 | 2 | 0 | R F | No | No |
17 | B | 11–20 | 1d | 0 | R F | No | No |
18 | B | 41–50 | 1d | 1 | R F C | Yes | No |
19 | B | 31–40 | 2 | 1 | R F K | Yes | No |
20 | B | 51–60 | 1d | 1 | R F K C | Yes | No |
21 | B | 31–40 | 1d | 0 | R F | No | No |
22 | B | 21–30 | 1 | 1 | R F | No | No |
23 | B | 31–40 | 1 | 0 | R F K Z | Yes | No |
24 | B | 31–40 | 1 | 0 | R F C | Yes | No |
25 | B | 51–60 | 2 | 0 | R | No | No |
26 | B | 31–40 | 1d | 2 | R F | No | No |
27 | B | 21–30 | 1d | 3 | R F | No | No |
28 | B | 51–60 | 1 | 1 | R F K C | Yes | No |
B: breakthrough infection; C: cough; EU: European Union; F: fever; K: conjunctivitis; N: naïve infection; ND: not done; R: rash; Z: coryza.
a Breakthrough infection was defined as a confirmed case of measles in an individual with history of vaccination and/or positive IgG levels (> 399 mIU/mL) in acute serum at or after onset of rash (if taken within 4 days), regardless of whether post-exposure prophylaxis was given or not.
b Fulfilled both clinical and laboratory criteria according to the EU case definition.
c Patient 12 had no history of vaccination against measles and no history of measles infection. This patient presented low levels of IgG (579 mIU/mL) at first sampling 5 days after onset of rash and had received post-exposure measles vaccine 7 days before onset of rash.
d Reported at least one dose of measles vaccine, not documented.