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. 2019 Jun 20;116(28):14002–14010. doi: 10.1073/pnas.1817255116

Fig. 6.

Fig. 6.

Prediction of the relative signaling potencies of well-characterized TCR ligands. Peptide-stimulation potencies (EC40 and EC50 values for IL-2 secretion) for CD4+ (Left) and CD8+ T cells (Right) (determined elsewhere in refs. 11, 52, and 53), plotted against the probability that at least one TCR triggering event (tmin ≥ 2 s) occurs at a single contact of r0 = 220 nm, that persists for tf = 120 s.