. 2019 Jun 20;116(28):14002–14010. doi: 10.1073/pnas.1817255116

Table 1.

Experimental parameters used in this study

Parameters	Value
Total cell area	415 μm²^*
TCR diffusion coefficient	0.05 μm² s⁻¹^†
Number of TCRs per cell	41,500^‡
Fraction of TCR segregation	0.62^†
CD45 to Lck ratio	2.5:1^†
Close contact radius	220 nm^§
Half-life of T cell–APC contacts	120 s^§
TCR triggering (minimum dwell time for triggering)	2 s^§^,^¶

References are given for measurements taken from the literature.

Weaver (65).

^{^†}

Experimentally determined in this study for Jurkat T cells.

^{^‡}

Experimentally determined in this study for CD4 T cells.

^{^§}

Cai et al. (49).

^{^¶}

Hui and Vale (40).