TABLE 1.
Effect of STZ-induced type I diabetes mellitus on heart rhythm.
| Control | STZ | |
| Characteristic of rat model | ||
| Body weight (g) | 322.50±22.4 | 191.00±37.4* |
| Heart weight (g) | 1.18±0.12 | 0.85±0.14† |
| Heart/body weight ratio | 3.59±0.32 | 4.19±0.35‡ |
| Blood glucose (mg/dl) | 101.91±10.5 | 533.33±45.1§ |
| Ex vivo ECG parameter | ||
| RR interval (s) | 0.196±0.009 | 0.238±0.022|| |
| PR interval (s) | 0.039±0.011 | 0.047±0.013¶ |
| QT interval (s) | 0.052±0.009 | 0.068±0.005# |
| QRS complex (s) | 0.0124±0.0003 | 0.0154±0.0002** |
(A) General characteristics of STZ-induced diabetic rats (n = 21) vs. age-matched controls (n = 22). (B) Ex vivo ECG parameter of STZ-induced type I diabetic rats (n = 4) compared to controls (n = 4). *Significantly different in body weight, †Significantly different in heart weight. ‡Significantly different in heart/body weight ratio. §Significantly different in blood glucose. ||Significantly different in RR interval. ¶Significantly different in PR interval. #Significantly different in QT interval. ∗∗Significant differently in QRS complex. Data are means ± SEM; P < 0.05.