Table 3:
Temporal comparison of serum PBDE and OH-PBDE concentrations across the three cohorts of Northern California womena
| 2008-2009 (n=25) | 2011-2012 (n=36) | 2014 (n=50) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| congener | MDLb | % >MDL |
GMb (GSD) |
MDLb | % >MDL |
GMb (GSD) |
MDLb | % >MDL |
GMb (GSD) |
| BDE-28 | 0.66 | 100% | 2.32 (1.68) |
0.77 | 78% | 1.18 (2.26) |
1.19 | 80% | 2.72 (2.31) |
| BDE-47 | 11.7 | 100% | 43.1 (1.7) |
5.85 | 100% | 25.8 (2.03) |
4.78 | 100% | 24.6 (2.02) |
| BDE-99 | 3.63 | 100% | 11.5 (1.82) |
4.92 | 61% | 5.04 (2.78) |
2.61 | 66% | 4.89 (2.78) |
| BDE-100 | 0.91 | 100% | 9.00 (1.86) |
1.08 | 97% | 4.6 (2.27) |
1.19 | 66% | 2.41 (3.55) |
| BDE-153 | 0.93 | 100% | 15.5 (1.82) |
1.54 | 97% | 10.9 (2.17) |
2.39 | 62% | 4.75 (3.81) |
| ∑5PBDEs | 85.8 (1.24) |
51.6 (1.29) |
43.6 (1.28) |
||||||
| 6-OH-BDE47 | 0.010 | 92% | 0.025 (2.4) |
0.002 | 61% | 0.004 (3.91) |
0.002 | 66% | 0.004 (4.04) |
| 5-OH-BDE47 | 0.012 | 84% | 0.028 (3.5) |
0.002 | 64% | 0.004 (5.00) |
0.002 | 50% | 0.0021 (5.50) |
a
abbreviations are as follows, MDL= method detection limit; GM=geometric mean, GSD=geometric standard deviation
b
units for BDE congeners are ng/g, while hydroxylated metabolites are ng/mL