Table 1.

Cox regression models of DFS

		Univariate		Multivariate
	Variable	Hazard Ratio (95% Confidence Interval)	P-value	Hazard Ratio (95% Confidence Interval)	P-value
Training Set	Immune Activation Score (log10 transformed)	0.1430 (0.03683– 0.5555)	0.00496*	0.1688 (0.04039–0.7054)	0.014758*
	Stage at Diagnosis	2.1227 (1.439– 3.131)	0.000147*	2.0310 (1.33617–3.0871)	0.000911*
	Age at Diagnosis	1.006 (0.9661– 1.048)	0.765	1.0363 (0.99081–1.0840)	0.119459
	Received Chemotherapy	0.4879 (0.1752– 1.359)	0.17	0.4660 (0.14512–1.4965)	0.199589
Validation Cohort	Immune Activation Score (log10 transformed)	0.2111 (0.06075–0.7335)	0.01440*	0.1939 (0.05451–0.6896)	0.011280*
	Stage at Diagnosis	1.628 (1.204–2.201)	0.00154*	1.6363 (1.18309–2.2632)	0.002920*
	Age at Diagnosis	1.013 (0.9812–1.045)	0.43200	1.0198(0.96152–1.0605)	0.696870
	Received Chemotherapy	0.6166 (0.1986–1.915)	0.40300	0.7696 (0.14986–3.9519)	0.753700

^*significant P-values