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a) The PET imaging and b) corresponding tumor uptake (%ID/g) of U87MG tumor-bearing mice by i.v. injection of SPB and SPB@POM. c) IR thermal imaging of U87MG tumor-bearing mice during 5 min of 808 nm laser irradiation after i.v. injection of SPB, SPB@POM and saline. d) Temperature rise profiles of the tumor as a function of the irradiation time. e) Tumor growth curves and f) survival rates of U87MG tumor-bearing mice subjected to varied treatments. *P<0.05, **P<0.01, ***P<0.001.
