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. 2019 Jul 15;14(7):e0218547. doi: 10.1371/journal.pone.0218547

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© 2019 Carrisoza-Urbina et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 3 — (A) Masson's trichrome stained section showing a stage IV granuloma surrounded by abundant fibrous tissue (yellow arrow) in a bovine adult. (B) Masson's trichrome stained section showing a stage III-IV granuloma, without a fibrous capsule, but with surrounding disorganized collagen fibers in a calf. White arrow indicates connective tissue of the lymph node capsule as a reference. (C and D) Von Kossa staining, 200x, exhibiting stage IV (adult) and stage III-IV (calf) granulomatous lesions, with calcium deposits dyed in black.