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. 2019 Jun 20;4(12):e125494. doi: 10.1172/jci.insight.125494

Figure 8. B cell recruitment to the lung after BeO exposure was independent of antigen and dependent on MyD88 signaling.

Figure 8

(A) Total numbers of B cells in the lungs of WT C57BL/6J (B6) and MD4 BCR–Tg (MD4) mice exposed to either PBS or BeO is shown. Cumulative data from 2 separate experiments having 5 mice per group are shown. (B) Total numbers of B cells in the lungs of WT C57BL/6J (B6), MyD88–/–, TLR9–/–, and STING–/– mice exposed to either PBS or BeO are shown. (C) CXCL13 (pg/ml) and (D) total protein (left), albumin (middle), and T1A (right) levels in the bronchoalveolar lavage fluid of WT C57BL/6J (B6), MyD88–/–, TLR9–/–, and STING–/– mice exposed to either PBS or BeO are shown. Data are representative of 3 independent experiments having 5 mice per group. Statistical significance was determined using a 2-way ANOVA, and the solid line and error bars depict the mean ± SEM. A P value of <0.05 was considered statistically significant.