Figure 5. CCR2 mediates NK cell migration in response to VV infection.

WT or Ccr2^–/– mice were infected with VV (5 × 10⁶ PFU, i.p.) or left uninfected as controls (Naive). Three days later, peritoneal fluid was harvested and assayed for DX5⁺CD3^– NK cells by flow cytometry. (A) FACS plots showing percentages of DX5⁺CD3^– NK cells in the peritoneal fluids. (B) The mean absolute NK cell numbers ± SD are shown (n = 3). (C) The viral titer in peritoneal fluid was measured by the standard plaque assay and the mean viral titers ± SD are shown (n = 4). **P < 0.01, 2-tailed Student’s t test.